Drug intelligence / Profile preview

Beijing Normal Univ. CAIX compound [68Ga]Ga-14

Development stage
Unknown
Lead developer
Beijing Normal University
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals
01

Overview

Beijing Normal Univ. CAIX compound [68Ga]Ga-14: sourced facts only. name: "[68Ga]Ga-14 bound recombinant human CAIX with high affinity (IC50 = 61 ± 9.5 nM)." [PMID:41544580]; target: "[68Ga]Ga-14 bound recombinant human CAIX with high affinity (IC50 = 61 ± 9.5 nM)." [PMID:41544580]; developer: "Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China." [PMID:41544580]; modality: "These findings identify [68Ga]Ga-14 as a highly promising CAIX-targeted PET tracer for sensitive detection of ccRCC, with potential for future theranostic applications." [PMID:41544580]

02

Targets

CA9 (Carbonic anhydrase IX)

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